My biotech client is expanding and looking to hire an Antibody Engineer – the ideal candidate will take on the following tasks:
- Conduct cutting-edge research to develop novel antibody-based candidate therapeutics including developing novel scaffolds and antibody libraries
- Perform panning and screening of phage and yeast display libraries
- Measure aggregation, solubility, stability and other parameters related to the druggability of candidate antibody therapeutics
- Produce purified candidate antibody therapeutics in quantities sufficient for animal studies
- Perform flow cytometry and sorting
- Perform bioinformatics analysis including sequence analysis
- Implement state-of-the art sample management and storage system
- Hire and direct technicians
The ideal candidate will possess the following qualities:
- PhD in Molecular Biology and ideally protein or antibody engineering experience
- Exceptional publication record and knowledge of B and T cell therapy, oncology immunotherapy, target discovery and validation, bioinformatics
- Some experience with phage or yeast display, flow cytometry and sorting, and protein biochemistry
- Experience managing and developing direct reports
- Knowledge of developing clinical biomarkers, predictors and associated assays